Bioinformatic Methods for Determining Resistance to Cancer Treatments
Invention Summary:
Determining resistance to chemotherapy treatments for specific types of cancer (e.g., prostate, lung, breast, etc.,) as early as possible can prolong patients' lives by enabling them to be treated with other, and hopefully, more effective treatments as soon as possible.
Researchers at Rutgers University have...
Published: 7/15/2024
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Inventor(s): Antonina Mitrofanova, Sukanya Panja, Sarki Abdulkadir, Vishal Kothari, Edward Schaeffer
Keywords(s): Bioinformatics, Biomarkers, Digital Health, Prostate Cancer
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences
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SAHMI: Microbiome-based screening method for cancer and other diseases
Screening methodology and principle data identifying differences in
microbiome diversity from disease state in pancreatic cancer
Invention Summary:
The microbiome plays an essential role in the prognosis and progression of disease and health, as seen in cancers like pancreatic cancer. Pancreatic cancer is rising in majority of cancer...
Published: 8/8/2022
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Inventor(s): Subhajyoti De, Bassel Ghaddar
Keywords(s): Anti-cancer, Bioinformatics, Biomarkers, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Cancer
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An Algorithm for Identification of Treatment-response Biomarkers to Chemotherapies
Invention Summary:
In the last decade, several computational methods have been successfully applied to understand cancer initiation and progression through integration of genomic and epigenomic data. However, despite recent advances in discovering a wide array of novel chemotherapy agents, identification of patients with poor and favorable response...
Published: 6/7/2022
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Inventor(s): Antonina Mitrofanova, Nusrat Epsi
Keywords(s): Bioinformatics, Biomarkers, Cancer biomarkers, Data Science, Digital Health
Category(s): Technology Classifications > Software & Algorithms, Technology Classifications > Software & Copyright, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Lightning-fast Genome Variant Detection
Invention Summary:
Current human whole genome sequencing projects produce massive amounts of data, often creating significant computational challenges. Different approaches have been developed for each type of genome variant and method of detection, necessitating users to run multiple algorithms to find variants.
Researchers at Rutgers University...
Published: 4/21/2024
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Inventor(s): Andrey Grigoriev, Sean Smith
Keywords(s): Bioinformatics, Gene editing
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences
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Novel Process for Early Diagnosis and Treatment of Diabetic
Invention Summary:
Sixty to seventy percent of diabetes patients suffer from the nerve disorder diabetic peripheralneuropathy (DPN), which causes pain, tingling, numbness in extremities and can lead to devastating (complications such as falls, amputations, muscle weakness, unsteady gait and foot ulcers. Current diagnostic methods for neuropathy...
Published: 4/21/2024
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Inventor(s): Nizar Souayah
Keywords(s): Bioinformatics, Diabetes & Metabolic Disorders
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Predicting Therapeutic Resistance to Tamoxifen in Cancer Treatment
Invention Summary:
Currently, patients with ER+ breast cancer are administered tamoxifen without considering their potential response to this therapy. Thousands of women take the tamoxifen only to discover that their tumors do not respond or that they develop resistance over time. The ability to screen patients ahead of the therapy administration...
Published: 5/15/2024
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Inventor(s): Antonina Mitrofanova, Sarra Rahem
Keywords(s): Bioinformatics, Breast Cancer, Data Science, Digital Health
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Cancer
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Panel & Software to Predict Therapeutic Resistance in Cancer Treatment
Invention Summary:
According to the American Cancer Society, prostate cancer is the second most common malignancy in men and the second-highest cancer-related cause of death in American men. Androgen deprivation therapy (ADT), which reduces or prevents male hormones (androgens) from interacting with cancer cells, has been shown to be beneficial in...
Published: 10/15/2022
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Inventor(s): Antonina Mitrofanova, Sukanya Panja
Keywords(s): Bioinformatics, Biomarkers, Cancer biomarkers, Digital Health, Prostate Cancer
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Novel Quantitative Analytical Tool for Assessing Neurological Functions in Human Subjects
Tracking statistical signals from both mental and physical activities
Invention Summary:
Cognitive Neuroscience research uses cortical-related activity to infer various functional and anatomical aspects of the brain. However, this is done in a rather disembodied way, discounting the feedback from bodily biorhythms. In contrast, fields like Behavioral...
Published: 6/13/2024
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Inventor(s): Elizabeth Torres
Keywords(s): Bioinformatics, Biosensor, Data Science, Networks, Neurological disorder & neuropathic pain, Rehabilitation, Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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