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MYC Program as a biomarker of response to treatment with Enzalutamide
Invention Summary:
Administration of Enzalutamide has been shown to improve patient survival overall, yet patients respond differently to the drug with nearly half either not responding or developing resistance over time. Unfortunately, patients that fail Enzalutamide treatment are left with no targeted therapeutic option, and progress to...
Published: 10/11/2024
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Inventor(s):
Keywords(s):
Category(s): Technology Classifications > Cancer, Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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Activity-Based Aptamers as Next-Generation Bioimaging Tools and Diagnostics
Invention Summary:
As more and diverse biomarkers are identified for critical pathophysiological processes, there is a growing need to develop easily applied, reliable, and adaptable diagnostic tools.
Rutgers researchers have developed a smart molecular toolbox that fulfill these criteria. This toolbox, termed the activity-based aptamer...
Published: 9/16/2024
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Inventor(s): Enver Izgu, Tushar Aggarwal
Keywords(s): Biosensor
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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SuperSelective PCR Primers
Structure of a SuperSelective primer for the detection and quantitation of rare mutant sequences in the presence of 1,000,000 wild-type sequences; and a demonstration that the number of amplification cycles required to generate a signal above background is inversely linearly proportional to the logarithm of the number of mutant molecules in the original...
Published: 10/9/2024
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Inventor(s): Salvatore Marras, Diana Vargas-Gold, Sanjay Tyagi, Fred Kramer
Keywords(s): Anti-cancer, Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Diagnostics
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Surgical Artificial Intelligence Ureteral Injury Prevention System for Robotic and Laparoscopic Surgery
Image legend: The software will offer surgeons a real‐time monitoring system for the position of the ureters
Invention Summary:
Overall incidence of significant ureteral injury in gynecologic and colorectal surgeries is 1.7% and 1.9%, respectively. The risk of injury is higher in cases with a complex history of prior surgery, radiation, inflammatory...
Published: 10/7/2024
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Inventor(s): Hussam Shwaib
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Medical Imaging, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Software & Algorithms
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Rutgers PerioCalc App
PerioCalc is a cutting-edge Periodontal Calculator app designed to educate users on the latest classification of Periodontal Diseases and Conditions.
Invention Summary:
Over 40% of American adults suffer from gum disease.
Researchers at Rutgers University have developed this app which provides an intuitive interface for healthcare providers...
Published: 6/28/2024
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Inventor(s): Georgios Kotsakis
Keywords(s):
Category(s): Technology Classifications > Dental, Technology Classifications > Diagnostics, Technology Classifications > Education, Technology Classifications > Software & Copyright
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Novel diagnostic/prognostic biomarkers for multisystem inflammatory syndrome
Fig 1. The potential added value of testing for novel biomarkers including FCGBP, MRC1, and LBP in children with MIS-C include the quick and accurate diagnosis, treatment, and prognosis.
Invention Summary:
The multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical need for timely, accurate disease...
Published: 4/21/2024
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Inventor(s): Maria Gennaro, Jeisac Guzmán Rivera, Dirk Moore
Keywords(s): Biomarkers
Category(s): Technology Classifications > COVID-19, Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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The HμB (High-Efficiency μ-Fluidic Barrier)
Figure 1. The Hμb being used with a conventional microscope stage.
Invention Summary:
In the pharmaceutical and cosmetics industries, it is pertinent to screen for safety and dosage efficacy of developed drugs and compounds. These experiments can be costly and use equipment that can only be operated by skilled technicians and...
Published: 6/13/2024
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Inventor(s): Maribel Vazquez, Juan Pena-Carvajal
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Research Tools
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Gel-Tethered Molecular Beacons for Detection of Microbes
Invention Summary:
Pathogen detection and characterization is a critical first step in the course of care for individuals suffering from these infectious diseases, and the speed by which this pathogen detection occurs can make all the difference between life or death for many patients. Currently, the gold standard for microbe quantification is either...
Published: 8/24/2023
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Inventor(s): Salvatore Marras, Xiaoguang Dai, Matthew Libera
Keywords(s): Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Rapid Diagnostics of Tick-borne Diseases
Invention Summary:
Tick-borne diseases are a major health problem in the United States. Among them, Lyme disease due to the Borrelia spp., Anaplasmosis due to Anaplasma spp., and Babesiosis caused by Babesia spp., account for a large number of cases occurring throughout the country. Although treatment is readily available to combat these pathogens,...
Published: 6/6/2023
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Inventor(s): Nikhat Parveen, Salvatore Marras
Keywords(s): Disease Animal Models, Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Methods of diagnosing B cell malignancies and detecting B cell malignancy relapse
Workflow schematic of the diagnostic platform for detecting B cell malignancies.
Invention Summary:
B cell malignancies comprise more than 50% of blood cancers and approximately 90% of all lymphomas. Existing technologies for the detection of B cell malignancies include modern imaging technologies, flow cytometry of B cell subpopulations, cytogenetic...
Published: 8/19/2024
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Inventor(s): Ping Xie, Jaeyong Jung, Roger Strair, Samantha Gokhale, Lauri Goodell, Amer Assal
Keywords(s): Cancer biomarkers
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences
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