Protein/peptide-based therapeutics are powerful medications, however their use is often hampered by very short half-lives and the necessity for intravenous or subcutaneous injections.
Researchers from Rutgers University and Massachusetts General Hospital have developed a novel method to deliver protein/peptide-based therapeutics via viral-mediated gene delivery or transplantation of genetically engineered cells. The expression of transduced genes and thus secretion/delivery of corresponding protein/peptide therapeutics can be achieved through various ways: 1) as a response to a normal physiological cue for optimal delivery; 2) in response to disease-related molecular signals; 3) in response to an external stimuli.
- Gene Therapy
- Cell Therapy
- Sustained drug release
- Controlled drug release
- Timed drug release
Intellectual Property & Development Status:
Patent pending. Available for licensing and/or research collaboration.