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Mobile Health Diagnostic for Schizophrenia
Invention Summary: Schizophrenia is a psychiatric disorder characterized by hallucinations, disorganized thought, delusions, and a decline in both mental and physical functioning. The disorder affects about 1% of the population. Early detection and treatment significantly improves patient response to treatment; and can prevent progression to full...
Published: 11/3/2022   |   Inventor(s): Thomas Papathomas, Attila Farkas
Keywords(s): Mental Health, Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Medical Devices, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
Method for Generating Memory T-cells In Vitro and Their Use in Immunotherapy
Invention Summary: Dendritic cell-based immunotherapies have been tested for the treatment of cancer patients with limited success. The limited success is probably due to the ineffective activation of specific T-cells by injected dendritic cells. In vitro generation of memory T-cells that can respond to cancer cells could circumvent ineffective T-cell...
Published: 11/3/2022   |   Inventor(s): Shigeko Yamashiro (Matsumura), Fumio Matsumura, Aya Matsumura
Keywords(s): Anti-cancer, Immunoassay
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Therapeutics
MAP Training my Brain
­​ ​ Invention Summary: Depression is a debilitating disorder that affects nearly one in five Americans in their lifetime, causing severe symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or working. It is widely accepted that either aerobic exercise or meditation alone can reduce symptoms...
Published: 11/1/2022   |   Inventor(s): Tracey Shors
Keywords(s): Mental Health
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Healthcare & Life Sciences
Expanding Human Primary Liver Tissues into Functional Organoids
­ ​ Invention Summary: Chronic liver diseases account for approximately two million deaths per year- one million due to complications of cirrhosis and one million due to viral hepatitis and hepatocellular carcinoma. Unfortunately, there are few treatment options for these conditions, and they commonly require organ transplants. The primary...
Published: 9/14/2022   |   Inventor(s): Hatem Sabaawy, Fredric Wondisford
Keywords(s): Drug Discovery/Screening
Category(s): Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Controlled Muscle-Specific Gene Delivery
​ ​ Treatment with the AAV gene therapy with doxycycline (B) induced expression of the target gene. Invention Summary: Adeno-associated virus (AAV) vector-based gene therapy has the potential to treat a number of rare diseases. However, only two AAV-based gene therapies have been approved by the FDA, primarily due to toxicity and lack of specificity. Researchers...
Published: 8/25/2022   |   Inventor(s): Renping Zhou
Keywords(s): Gene editing
Category(s): Technology Classifications > Gene Therapy, Technology Classifications > Healthcare & Life Sciences
Modified Simmons Catheter
​ ​ Neurointerventions with improved success Invention Summary: The global neurovascular catheter market size was valued at USD 2.88 billion in 2020 and is expected to expand at a compound annual growth rate of 6.7% from 2021 to 2028. Neurointerventionalists, interventional radiologists, cardiologists, and vascular surgeons often can have...
Published: 8/25/2022   |   Inventor(s): Amit Singla
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
Enzyme Catalyzed Toehold Mediated Strand Displacement (TMSD)
​ ​ Invention Summary: Toehold mediated strand displacement (TMSD) is widely used in nanotechnology applications such as DNA nano-circuits and devices. The toeholds which are small single‐stranded DNA overhangs, are often utilized in kinetically controlled complex biochemical circuits. Existing toehold mediated strand displacement (TMSD)...
Published: 8/12/2022   |   Inventor(s): Smita Patel, Laura Johnson, Gayatri Patel, Anupam Singh
Keywords(s): Biosensor, Catalysts, Nanotechnology
Category(s): Technology Classifications > Research Tools, Technology Classifications > Healthcare & Life Sciences
Nitrous Oxide Sedation for the Dental Team (Video and DVD)
Invention Summary: Nitrous Oxide Sedation for the Dental Team DVD is an instructional video for dental practitioners such as dental hygienists, assistants, dentists and students. The DVD teaches and shows how to monitor Nitrous Oxide Sedation (NOS). Video Content: Dr. Vaishali Singhal created the NOS DVD in response to a lack of supplemental educational...
Published: 8/2/2022   |   Inventor(s): Vaishali Singhal, Matthew Rosenthal
Keywords(s): Video
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Dental, Technology Classifications > Education, Technology Classifications > Healthcare & Life Sciences
Novel ChABC formulation with machine learning-guided automation
​ ​ Invention Summary: Spinal cord injury (SCI) leads to the formation of scar tissue. The scarring leads to the toughening of the extracellular matrix, or the cellular environment. One of the major concerns of SCI is the prevention of neuronal connection recovery, which can lead to paralysis or reduced control of the nervous system. For...
Published: 8/2/2022   |   Inventor(s): Adam Gormley, Matthew Tamasi, Shashank Kosuri, Michael Webb, Carlos Borca, Roshan Patel
Keywords(s): Biomaterials, Polymers & Composites, Proteins, Spinal Cord
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Software & Algorithms, Technology Classifications > Therapeutics
PKC412 restores functionality of the keratin cytoskeleton in the skin disorder epidermolysis bullosa simplex
­​ ​ Invention Summary: Epidermolysis bullosa simplex (EBS) is a highly penetrant genetic condition that causes fragility of skin keratinocytes resulting in fluid-filled skin blisters that erode upon scratching or minor pressure on the skin. There is no good cure for EBS, and treatment typically involves preventive and/or supportive care...
Published: 7/21/2022   |   Inventor(s): Bishr Omary, Thomas Magin, Jacques Roberge, Katrin Rietscher
Keywords(s): Dermatology
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Rare Disease
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