Use Of Generative AI and Impedance Cytometry for Ionic Microscopy and Cell Imaging

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Invention Summary:

Traditional cell identification methods, often relying on complex microscopy or fluorescence-activated cell sorting (FACS), are time-consuming, and require expensive and bulky instruments. This highlights the need for more precise, rapid, and affordable diagnostic tools. 

Rutgers researchers have developed a novel system combining impedance flow cytometry with generative AI that automatically classifies biological cells. This system measures impedance variations as cells pass through an electric field and uses a trained neural network to generate virtual cell images, eliminating the need for traditional microscopy.  Additionally, the technology enables population-level cell classification by analyzing impedance patterns and probability density functions of different cell types. This approach allows for real-time, high-throughput, and label-free identification of various cells, including various cancer cell types, enabling early cancer diagnosis.

Market Applications:

  • Medical Diagnostics & Cancer Research 

  • Biopharmaceutical Development  

  • Point-of-Care Testing & Lab Automation 

Advantages:

  • High-Speed Analysis: Rapid, real-time cell classification without extensive sample preparation. 

  • Compact & Cost-Effective: Enables portable, point-of-care applications. 

  • Machine Learning Integration: Improves accuracy and consistency in cell classification. 

 

Intellectual Property & Development Status: Provisional application filed. Patent pending. Available for licensing and/or research collaboration. For any business development and other collaborative partnerships, contact:  marketingbd@research.rutgers.edu

Patent Information:
Licensing Manager:
Lisa Lyu
Associate Director, Licensing
Rutgers, The State University of New Jersey
848-932-4539
lisa.lyu@rutgers.edu
Business Development:
Eusebio Pires
Senior Manager, Technology Marketing & Business Development
Rutgers, The State University of New Jersey
ep620@research.rutgers.edu
Keywords: