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Novel Maturation‐defective Attenuated Chlamydia Vaccine
­​ ​ Invention Summary: Millions of American men and women are infected with Chlamydia each year. Without proper treatment, a substantial proportion of chlamydia-infected women may develop infertility and other health problems. To date, no Chlamydia vaccine is available. Chlamydia is an obligate intracellular bacterium with a unique...
Published: 5/26/2022   |   Inventor(s): Huizhou Fan
Keywords(s): Gene editing
Category(s): Technology Classifications > Vaccine, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
Fluorescent Probe for Bacterial Cell Imaging and Screening of New Antibacterial Drugs
Visualization of the impact of FtsZ-targeting drug treatment in both Gram-positive and Gram-negative bacterial strains using BOFP. Bacteria were labeled with BOFP for 5 minutes just prior to visualization. Differential interference contrast (DIC) shows unstained bacteria and fluorescence shows BOFP-labeled bacteria. Invention Summary: At least 2.8...
Published: 5/11/2020   |   Inventor(s): Daniel Pilch, Edgar Ferrer-Gonzalez, Edmond LaVoie
Keywords(s): Drug Discovery/Screening
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease, Technology Classifications > Research Tools
DNA Nanodevices for Point-of-Care Testing
DNA nanodevice can detect 0.1 nm microRNA Invention Summary: Point-of-Care (POC) testing is defined as a simple operated, easy-to-read, rapid and low-cost medical diagnosis that can be used by non-specialists at home, in the field or on an ambulance. It provides timely diagnostic results, enabling early diagnosis of diseases, protective therapy...
Published: 1/7/2020   |   Inventor(s): Jinglin Fu, Sung Won Oh, Adriana Pereira
Keywords(s): Bioengineering scaffolds, Biomarkers, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > COVID-19, Technology Classifications > Research Tools, Technology Classifications > Infectious Disease
Biosensors for Real-Time Antimicrobial Susceptibility Testing
(A) A schematic of the biosensor. (B) Real time detection of the effect of antibiotics (Ampicillin) on the growth of E. coli. (C) and (D) Real time detection of the effect of antifungal agents Miconazole and Amphotericin B on the growth of yeast. Invention Summary: Antimicrobial resistance (AMR) is becoming a major global-health concern. Traditional...
Published: 5/2/2018   |   Inventor(s): Yicheng Lu, Pavel Reyes, Steven Zheng, Andrew Zheng, Keyang Yang
Keywords(s): Biosensor
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Research Tools, Technology Classifications > Electronics/Semiconductor, Technology Classifications > Infectious Disease