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A Quick Estimation of Human Arterial Stiffness Using HRV
Invention Summary: Cardiovascular diseases (CVDs) are the leading cause of deaths worldwide. Arterial elasticity is an important indicator of existing cardiovascular risks of developing CVDs. Reduced arterial elasticity or increased arterial stiffness is known to be associated with hypertension, myocardial infarction and stroke. Being able to measu...
Published: 8/14/2017   |   Inventor(s): Evgeny Vaschillo, Bronya Vaschillo
Category(s): Diagnostics, Software
Novel Quantitative & Objective Analytical Tool for Detecting Neurodevelopmental Delays in Infants
Invention Summary: Neurodevelopmental disorders (e.g. autism) are on the rise. They are the byproduct of a lengthy maturation process that starts at conception and manifests disarray with high certainty during infancy, when dysfunction of the child’s nervous systems becomes apparent to the naked eye. By three years of age, observational diagn...
Published: 8/14/2017   |   Inventor(s): Elizabeth Torres
Category(s): Life Sciences, Diagnostics
An Underwater Acoustic Lens
Invention Summary: Sending and receiving information below the water surface is important but challenging. Techniques such as Sonar use acoustic waves in water to transmit information. Acoustic metamaterials enable Sonar devices to control, direct and manipulate sound waves for increased functionality and higher efficiency. Specifically, acoustic l...
Published: 8/14/2017   |   Inventor(s): Andrew Norris, Xiaoshi Su
Category(s): Physical Sciences, Engineering
Novel Quantitative Analytical Tool for Assessing Neurological Functions in Human Subjects
Tracking statistical signals from both mental and physical activitiesInvention Summary: Cognitive Neuroscience research uses cortical-related activity to infer various functional and anatomical aspects of the brain. However, this is done in a rather disembodied way, discounting the feedback from bodily biorhythms. In contrast, fields like Behaviora...
Published: 8/11/2017   |   Inventor(s): Elizabeth Torres
Category(s): Life Sciences, Diagnostics
Nanoelectronic Barcoding of Microparticles For Multiplexed Molecular Analysis
Invention Summary:Capability of detecting multiple protein and nucleic acid biomarkers is crucial to disease diagnosis and precision medicine. Barcoding of microparticles is one of the most common approaches for enabling multiplexed molecular assays. Although optical and plasmonic methods for barcoding particles have been developed, instrumentation...
Published: 8/7/2017   |   Inventor(s): Mehdi Javanmard
Keywords(s): Biosensor, Biosensors
Category(s): Life Sciences, Diagnostics, Materials
Drug Candidates for Autoimmune Diseases: Cell Penetrating Peptides that Inhibit IRF5 Activity
Invention Summary:Interferon regulatory factor 5 (IRF5) is a transcription factor that regulates key intracellular signaling pathways that result in proinflammatory cytokine expression. Emerging preclinical and clinical studies have indicated that IRF5 could be a drug target for inflammation and autoimmune diseases, especially systemic lupus erythe...
Published: 8/7/2017   |   Inventor(s): Betsy Barnes
Category(s): Life Sciences, Therapeutics
Gigantus1, A Newly Identified Gene Target for Improved Plant Growth and Yield in Agricultural Applications
Gts1- knockout plants (Gts-1) displayed faster germination and increased growth compared to wild-type (WT) plants.Invention Summary:Rutgers scientists discovered a new gene Gigantus1 (Gts1) in Arabidopsis thaliana, which significantly influences seed germination, growth and biomass accumulation in plants. The protein product GIGANTUS1 (GTS1) belong...
Published: 8/7/2017   |   Inventor(s): Simeon Kotchoni
Category(s): Agriculture, Plants, Berries, Fruit
Human Organoid Culture
Invention Summary:An organoid is a small three-dimensional (3-D) tissue structure that highly resembles the in vivo organ from which it originated. New technology developed at Rutgers Cancer Institute of New Jersey enables researchers to generate organoids from both normal and cancerous tissues of patients. Using this human organoid culture method,...
Published: 8/7/2017   |   Inventor(s): Hatem Sabaawy, Monica Bartucci
Category(s): Life Sciences, Diagnostics
Novel Cationic Amphiphiles as Antimicrobial Therapeutics & Additives in Food Packaging, Household, and Personal Care Products
Schematics showing the potential interactions between cationic amphiphiles with gram-positive and –negative bacterial membranes.Invention Summary:The emergence of antibiotic resistance drives the need for antibacterial agents that maintain efficacy against wildtype and multi-drug resistant bacteria. Naturally occuring antimicrobial peptides (...
Published: 8/7/2017   |   Inventor(s): Kathryn Uhrich, Allison Faig
Category(s): Life Sciences, Therapeutics
Invention Summary:Raman spectroscopy is a valuable analytical tool that employs vibration patterns for the identification of molecules. However, it is limited due to the low scattering cross section of most Raman active molecules, which leads to low sensitivity. Surface-enhanced Raman spectroscopy (SERS) increases the intensity of Raman signals by ...
Published: 8/7/2017   |   Inventor(s): Laura Fabris, Swarnapali Indrasekara
Keywords(s): Biomedical Imaging, Gold Nanoparticles, Imaging, Raman Spectroscopy, Spectroscopy
Category(s): Physical Sciences, Electronics
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